(3β,5α)-4,4-Dimethylcholesta-8,14-dien-3-ol is a meiosis-activating sterol isolated from from human follicular fluid and bull testes and the synthesis of two closely related C29 sterols.
ChEBI: A cholestanoid that is 5alpha-cholesta-8,14-dien-3beta-ol bearing two additional methyl substituents at position 4.
4,4-dimethyl-cholest-8(9), 14-dien-3β-ol (Dihydro follicular fluid meiosis-activating sterol (FF-MAS)) plays a role in triggering the initiation of meiosis in cultured oocytes of mice in vitro. It is an intermediate of the Kandutsch-Russell (K-R) pathway.
