ChemicalBook Product Catalog API Drug metabolism Blosozumab

Blosozumab

Chemical Properties

form	Liquid
color	Colorless to light yellow

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Animal Model:	Sprague-Dawley rats ^[2]
Dosage:	1, 10, and 100 mg/kg
Administration:	Intravenous injection (i.v.), once every 3 days (5-week study) or once weekly (6-month study)
Result:	Observed the bone anabolic effects. Showed significant bleeding and morbidity at 100 mg/kg. Decreases in the numbers of platelets. Increased number of bone marrow megakaryocytes at 100 mg/kg.