4-KETORETINOL activate gene expression through binding to nuclear receptor proteins. They are useful for treating leukemia, lymphoma, squamous cell carcinoma, deep (cystic) acne, psoriasis, and photodamaged or aging skin.
ChEBI: All-trans-4-oxoretinol is a retinoid that is all-trans-retinol in which the hydrogens at position 4 have been replaced by an oxo group. It has a role as an antineoplastic agent. It is a retinoid, a cyclic ketone, an enone and a primary allylic alcohol. It is functionally related to an all-trans-retinol.
