4-Chlorophenylboronic acid pinacol ester can be used as a reagent in Suzuki-Miyaura cross-coupling reaction to form C-C bonds by reacting with different aryl halides over palladium catalysts.
It can also be used as a reactant:
- To prepare 2-(4-chlorophenyl)-4H-chromen-4-one by treating with 4-chromanone via one-pot palladium-catalyzed dehydrogenation and oxidative boron-Heck coupling reaction.
- In the ligand-enabled C-H bond activation reaction in the presence of a palladium catalyst.
- To synthesize biaryl amides via Cu-catalyzed C-H bond coupling of aryl arylamides.
