腺苷5'-三磷酸二钠盐水合物
腺苷5'-三磷酸二钠盐水合物 性质
| 熔点 | 176 °C (dec.)(lit.) |
|---|---|
| 储存条件 | -20°C |
| 溶解度 | 在水中的溶解度为50mg/mL，透明，无色 |
| 形态 | 粉末 |
| 酸度系数(pKa) | (1) 4.0, (2) 6.5 |
| 颜色 | 白色 |
| 生物来源 | microbial (Corynebacterium sp.) |
| 水溶解性 | Soluble in water. |
| 最大波长(λmax) | 259 nm |
| 敏感性 | Light Sensitive & Hygroscopic |
| Merck | 14,155 |
| BRN | 3585462 |
| 稳定性 | 吸湿性、温度敏感 |
| InChIKey | NTBQNWBHIXNPRU-MSQVLRTGSA-L |
| CAS 数据库 | 34369-07-8 |
腺苷5'-三磷酸二钠盐水合物 用途与合成方法
ATP disodium salt hydrate (5mM; 1 hour) co-treatment with LPS (1 μg/ml) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.
ATP disodium salt hydrate (2 mM; 0.5-24 hours) induces secretion of interleukin 1β, KC and MIP-2 from bone marrow derived macrophages (BMDMs) in vitro in a caspase-1 activation-dependent manner.
ATP disodium salt hydrate stimulats cytokine and chemokine secretion and inflammasome activation directly and indirectly induces in vitro neutrophil chemotaxis.
ATP disodium salt hydrate (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.
ATP disodium salt hydrate induces the secretion of IL1β, KC and MIP-2 and neutrophils recruitment in vivo.
| Animal Model: | Four-week-old Kunming mice (18-22 g) |
| Dosage: | 50 mg/kg |
| Administration: | Intraperitoneal injection, before bacterial ( E. coli ) challenge |
| Result: | Protected mice from bacterial infection. |
腺苷5'-三磷酸二钠盐水合物 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025-02-05 | L14522 | 腺苷-5'-三磷酸二钠盐水合物, 99%, water <10% | 34369-07-8 | 1g | 485 |
| 2025-02-05 | L14522 | 腺苷-5'-三磷酸二钠盐水合物, 99%, water <10% | 34369-07-8 | 5g | 1841 |
