S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O

Dextromethadone-D3 is an impurity of Dextromethadone (CAS #: 5653-80-5). Dextromethadone is used in therapy for treating or preventing depression or other mood diseases.

ChEBI: Dextromethadone is a 6-(dimethylamino)-4,4-diphenylheptan-3-one that has (S)-configuration. It is the less active enantiomer of methadone and has very little activity on opioid receptors and mainly responsible for the inhibition of hERG K+ channels and thus for cardiac toxicity. The drug is currently under clinical development for the treatment of major depressive disorder. It has a role as a NMDA receptor antagonist and an opioid analgesic. It is an enantiomer of a levomethadone.