CA-5f (40 mg/kg, ip, every 2 days for up to 30 days) is well tolerated, and potently inhibits the growth of tumor in nude mice bearing A549 lung cancer cells.
CA-5f (40 mg/kg, ip) suppresses autophagic flux and induces apoptosis in nude mice bearing A549 lung cancer cells.
| Animal Model: | < td class="col2"> Nude mice bearing A549 lung cancer cells
| Dosage: | 40 mg /kg |
| Administration: | Injected via caudal vein, every 2 days for up to 30 days < /td> |
| Result: | Significantly suppressed tumor volume and weight in mice, increased the number of apoptotic cells in mice . |
