(-)-1,2-BIS[(2R,5R)-2,5-DIMETHYLPHOSPHOLANO]BENZENE

1. The DUPHOS family of catalysts is highly efficient for the asymmetric hydrogenation of various substituted cetamidoacrylates and enol acetates yielding products of high enantiomeric excesses.
2. Efficient ligand for the asymmetric hydrogenation of imines, enamines, and enamides.
3. Asymmetric hydrogenation of vinyl alcohols.
4. Catalyst used for the asymmetric hydrogenation of enol phosphonates.
5. Asymmetric hydrogenation of allylic alcohols.
6. Ligand for the catalytic asymmetric [4+1] cycloaddition of vinylallenes with CO.
7. Ligand for the Rh-catalyzed asymmetric enyne cycloisomerization.
8. Catalytic enantioselective addition of dialkylzinc to N-Diphenylphosphinoylimines.

1,2-Bis[(2R,5R)-2,5-dimethyl-1-phospholanyl]benzene is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. It is used as highly efficient privileged ligands.