N-Methyl-1H-imidazole-4-ethanamine dihydrochloride

2-(1H-Imidazol-5-yl)-N-methylethanamine is a metabolite of histamine.

ChEBI: N-alpha-Methylhistamine is an aralkylamine.

Tetrahedron, 23, p. 239, 1967 DOI: 10.1016/S0040-4020(01)83305-6

Potent histamine agonist, particularly at H 3 receptors (potency relative to histamine is 81, 185, and 270% at H 1 , H 2 and H 3 respectively). Also displays agonist properties at H 4 receptors to which it binds with moderate affinity (K i = 23 nM).