6-(BETA-D-2-DEOXYRIBOFURANOSYL)-3,4-DIHYDRO-8H-PYRIMIDO-[4,5-C][1,2]OXAZIN-7-ONE

Deoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one (Compound dP) exhibits mutagenicity for Escherichia coli and Salmonella typhimurium, that induces the conversion between GC and AT through replication error. eoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one is stable in Escherichia coli, and can be detected at wavelength >300 nM[1].

[1] Negishi K, et al., The mechanism of mutation induction by a hydrogen bond ambivalent, bicyclic N4-oxy-2'-deoxycytidine in Escherichia coli. Nucleic Acids Res. 1997 Apr 15;25(8):1548-52. DOI:10.1093/nar/25.8.1548