Tetraspanin-6 is a protein encoded by the TSPAN6 gene in humans. It is also referred as T245, TM4SF6 and TSPAN-6. It belongs to the transmembrane 4 superfamily and is mapped to chromosome Xq22. Tetraspanins are a group of hydrophobic proteins consisting of four transmembrane domains and two extracellular loops. Some are cell specific while others are very ubiquitous. It interacts with various different types of proteins such as integrins, membrane receptors, as well as intracellular signaling molecules.
