Solubility: 162 mg/L in water (30°C), soluble in acetonitrile, chloroform, ethanol, ethyl acetate, and xylene. Stability: Stable to sunlight and stable in neutral and alkaline solutions.
(Z)-Fermizone is a fungicide used in wheat and rice crops
ChEBI: A member of the class of pyrimidines that is 2-hydrazino-4,6-dimethylpyrimidine in which the two amino hydrogens are replaced by a 1-(2-methylphenyl)ethylidene group. It is used for the control of fungal diseases in rice.
Ferimzone is commercially produced through a multi-step synthesis involving pyrimidinone and hydrazone chemistry. Its industrial synthesis begins with the preparation of a 4,6-dimethylpyrimidin-2(1H)-one core, which is then reacted with (Z)-2′-methylacetophenone hydrazone to form the active hydrazone linkage. This step involves condensation under controlled temperature and solvent conditions to ensure the formation of the desired (Z)-isomer, which is critical for biological activity. The reaction is typically catalysed by acid or base and followed by purification steps such as recrystallization or chromatography to achieve high purity.
Disrupts membrane function. Thought to inhibit mycelial growth and spore germination.
