OTS964 hydrochloride (intravenously; 40 mg/kg on days 1, 4, 8, 11, 15, and 18) makes tumors shrinking even after the treatment and finally revealing complete regression[1].
OTS964 hydrochloride (oral administration; 50 or 100 mg/kg/day for 2 weeks) ultimately achieves complete tumor regression[1].
| Animal Model: | Nude mice bearing LU-99 lung cancer cells[1] |
| Dosage: | 40 mg/kg |
| Administration: | Intravenously; on days 1, 4, 8, 11, 15, and 18 |
| Result: | The tumors continued shrinking even after the treatment and finally revealed complete regression.
|
| Animal Model: | Nude mice bearing LU-99 lung cancer cells[1] |
| Dosage: | 50 or 100 mg/kg |
| Administration: | Oral administration; once every day for 2 weeks |
| Result: | Achieved complete tumor regression.
|
