L-N5-(1-IMINOPROPYL) ORNITHINE (HYDROCHLORIDE)

Nitric oxide synthase (NOS) catalyzes the conversion of L-arginine to nitric oxide (NO) and citrulline. Methyl-L-NIO (hydrochloride) is a competitive nitric oxide synthase (NOS) inhibitor that competes with L-arginine for the amino acid binding site. It is a more potent inhibitor of nNOS (K_i = 3.0 μM) than eNOS (K_i = 10.0 μM) or iNOS (K_i = 9.5 μM).