White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Poria cocos.
Polyporenic acid C is a lanostane-type triterpenoid isolated from P. cocos. Polyporenic acid C induces cell apoptosis through the death receptor-mediated apoptotic pathway without the involvement of the mitochondria. Polyporenic acid C is promising agent for lung cancer therapy[1].
Polyporenic acid C is a lanostane-type triterpenoid isolated from P. cocos. It induces apoptosis through the death receptor-mediated apoptotic pathway without the involvement of mitochondria. It has the potential to be used in lung cancer research.
PARP | Caspase | PI3K | Akt | p53
[1] Ling H, et al. Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells.Mol Carcinog.2009 Jun;48(6):498-507. DOI:
10.1002/mc.20487
