1-Palmitoyl-2-stearoyl-3-oleoyl-
rac-glycerol is a triacylglycerol that contains palmitic , stearic , and oleic acid at the
sn-1,
sn-2, and
sn-3 positions, respectively. It has been detected in RAW 264.7 cells by neutral loss MS.
1 Increased serum levels of 1-palmitoyl-2-stearoyl-3-oleoyl-
rac-glycerol are a potential biomarker for non-alcoholic fatty liver disease (NAFLD).
2
1-Palmitoyl-2-stearoyl-3-oleoyl-rac-glycerol (1-Palmitin-2-stearin-3-olein), a compound used in the study of changes in diglyceride and triglyceride molecular species in cells, was analyzed by neutral loss mass spectrometry and its content was found to change after cell activation.
1. Murphy, R.C., James, P.F., McAnoy, A.M., et al. Detection of the abundance of diacylglycerol and triacylglycerol molecular species in cells using neutral loss mass spectrometry Anal. Biochem. 366(1),59-70(2007).
2. Orei, M., Hytylinen, T., Kotronen, A., et al. Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids Diabetologia 56(10),2266-2274(2013).
