Sphinganine (d17:0) (hydrochloride)

Sphinganine (d17:0) is a synthetic bioactive sphingolipid.1 It is active against C. glabrata and C. albicans with a minimum fungicidal concentration (MFC) value of 0.5 µg/ml for both. Sphinganine (d17:0) has commonly been used as an internal standard for the detection of sphingolipids in chromatographic and mass spectrometry applications.2,3WARNING This product is not for human or veterinary use.

[1] KARIN THEVISSEN . Fungicidal activity of truncated analogues of dihydrosphingosine[J]. Bioorganic & Medicinal Chemistry Letters, 2008, 18 13: Pages 3728-3730. DOI: 10.1016/j.bmcl.2008.05.067
[2] STEFKA SPASSIEVA. Combination of C(17) sphingoid base homologues and mass spectrometry analysis as a new approach to study sphingolipid metabolism.[J]. Methods in enzymology, 2007, 434: 233-241. DOI: 10.1016/s0076-6879(07)34012-3
[3] FENG QU. Sphingolipids as new biomarkers for assessment of delayed-type hypersensitivity and response to triptolide.[J]. PLoS ONE, 2012: e52454. DOI: 10.1371/journal.pone.0052454