[1,1′-Biphenyl]-3-sulfonyl fluoride, 4′-[[[(1,4-dihydro-6-methyl-4-oxo-1-phenyl-3-pyridazinyl)carbonyl]amino]methyl]-3′,5′-difluoro-
[1,1′-Biphenyl]-3-sulfonyl fluoride, 4′-[[[(1,4-dihydro-6-methyl-4-oxo-1-phenyl-3-pyridazinyl)carbonyl]amino]methyl]-3′,5′-difluoro-
英文名称:[1,1′-Biphenyl]-3-sulfonyl fluoride, 4′-[[[(1,4-dihydro-6-methyl-4-oxo-1-phenyl-3-pyridazinyl)carbonyl]amino]methyl]-3′,5′-difluoro-
CAS号:3033748-20-5
分子式:C25H18F3N3O4S
分子量:513.49
EINECS号:
Mol文件:3033748-20-5.mol
![[1,1′-Biphenyl]-3-sulfonyl fluoride, 4′-[[[(1,4-dihydro-6-methyl-4-oxo-1-phenyl-3-pyridazinyl)carbonyl]amino]methyl]-3′,5′-difluoro- 结构式](https://img.chemicalbook.com/CAS/20240320/GIF/3033748-20-5.gif)
[1,1′-Biphenyl]-3-sulfonyl fluoride, 4′-[[[(1,4-dihydro-6-methyl-4-oxo-1-phenyl-3-pyridazinyl)carbonyl]amino]methyl]-3′,5′-difluoro- 性质
| 密度 | 1.41±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) |
|---|---|
| 溶解度 | Acetonitrile: Soluble DMSO: Soluble |
| 酸度系数(pKa) | 6.68±0.20(predicted) |
| 形态 | Solid |
| 颜色 | White to off-white |
[1,1′-Biphenyl]-3-sulfonyl fluoride, 4′-[[[(1,4-dihydro-6-methyl-4-oxo-1-phenyl-3-pyridazinyl)carbonyl]amino]methyl]-3′,5′-difluoro- 用途与合成方法
Anticancer agent 126 (compound 12) 是一种具有抗癌作用的 WDR5 抑制剂。Anticancer agent 126 破坏细胞中 WDR5-MYC 相互作用并减少 MYC 靶基因表达。
