Cholest-5-en-3-ol (3β)-, 3-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoate]

Biotin-cholesterol is a biotinylated form of Cholesterol (HY-N0322). Biotin-cholesterol can be used in the synthesis of biotin-conjugated liposomes and micelles for drug delivery[1].

[1] Ravi S Shukla, et al. Development of Streptavidin-Based Nanocomplex for siRNA Delivery. Mol Pharm. 2013 Dec 2;10(12):4534-45. DOI:10.1021/mp400355q
[2] LING T, LANG W H, MARTINEZ-MONTEMAYOR M M, et al. Development of ergosterol peroxide probes for cellular localisation studies†[J]. Organic & Biomolecular Chemistry, 2019, 21: 5223-5229. DOI: 10.1039/c9ob00145j
[3] LI W, DENG L, MOOSA B, et al. “Nail” and “comb” effects of cholesterol modified NIPAm oligomers on cancer targeting liposomes†[J]. Biomaterials Science, 2014, 4: 476-483. DOI: 10.1039/c3bm60222b