Coclaurine is a white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents.
Coclaurine is a tetrahydroisoquinoline alkaloid with anti-aging activity,used as a nicotinic acetylcholine receptor antagonis.
ChEBI: (R)-coclaurine is a coclaurine. It is an enantiomer of a (S)-coclaurine.
An intracerebroventricular injection of (+)-Coclaurine (d-Coclaurine; 50 μg) produces a slight increase in 3,4-dihydroxyphenylacetic acid level and a significant increase in homovanillic acid level in the mouse striatum. (+)-Coclaurine blocks postsynaptic but not presynaptic dopamine receptors in the mouse striatum[2].
