Lisinopril-d5 is intended for use as an internal standard for the quantification of lisinopril by GC- or LC-MS. Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor (IC50 = 1.2 nM). It reduces the formation of endothelin-1 and increases nitric oxide in human vascular endothelial cells. Lisinopril inhibits the pressor response to angiotensin I in anesthetized rats and dogs (ID50s = 2.3 and 6.5 μg/kg in rat and dog, respectively).
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(S)-Lisinopril-d5 is a labeled analogue of (S)-Lisinopril (L468985), an orally active angiotensin-converting enzyme (ACE) inhibitor.
Labelled Lisinopril, intended for use as an internal standard for the quantification of Lisinopril by GC- or LC-mass spectrometry
(S)Lisinopril-D5 can be Labeled , it is an orally active angiotensin-converting enzyme (ACE) inhibitor , intended for use as an internal standard for the quantification of Lisinopril by GC- or LC-mass spectrometry.
