Minalrestat (Oral gavage, 10 mg/kg/day, for 30 days) corrects the decreased microvascular reactivity in diabetic rats[1].
Minalrestat (Oral gavage, 10 mg/kg) restores the reduced number of leukocytes adhered and migrated leukocytes in postcapillary venules in diabetic rats[2].
| Animal Model: | Alloxan (40 mg/kg i.v.)-induced diabetic rats[1] |
| Dosage: | 10 mg/kg/day |
| Administration: | Oral gavage, for 30 days. |
| Result: | Restored the decreased microvascular reactivity. |
