LY288513 (3, 10 mg/kg, i.p.; 10, 30 mg/kg, p.o.) produces an anxiolytic-like action in mice[3].
LY288513 (1000 mg/kg, p.o.) potentiates the effects of a CNS depressant, slightly lowered body temperature, and had modest sedative effects only at the highest dose examined[3].
| Animal Model: | Male CD-l mice[3] |
| Dosage: | 3, 10 mg/kg; 10, 30 mg/kg |
| Administration: | I.p.; p.o. |
| Result: | Displayed anxiolytic-like effects in the elevated plusmaze.
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