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Tamoxifen

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10540-29-1 Basic informationMore
USE
Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells. Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response mo difiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Lastest Price from Tamoxifen manufacturers
  • Tamoxifen
  • US $3.00-865.00/g
  • CAS:10540-29-1
  • Min. Order: 1g
  • Purity: 99.99%
  • Supply Ability: 1000kg
  • 2024-04-24

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  • Company Name:TargetMol Chemicals Inc.
  • Tel:021-33632979 15002134094
  • Products Intro:Product Name:Tamoxifen
    CAS:10540-29-1
    Package:1 g;1 mL;100 mg;500 mg More...
  • CB Index:58
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  • Company Name:Suzhou Unite pharmTech Co., Ltd ,
  • Tel:792-3901125 13222993784
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    Purity:99% HPLC Package:25k,5KG;1KG More...
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  • Company Name:Chembest Research Laboratories Limited
  • Tel:021-20908456
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    CAS:10540-29-1
    Purity:99%+ Package:1g;5g;10g;50g;100g;500g;1kg Remarks:C14214 More...
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  • Company Name:Energy Chemical
  • Tel:021-021-58432009 400-005-6266
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    Purity:98% Package:1g;5g Remarks:NULL More...
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  • Company Name:Adamas Reagent, Ltd.
  • Tel:400-6009262 16621234537
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    CAS:10540-29-1
    Purity:对照品 Package:10mg~500mg Remarks:AC00011900 More...
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