Tamoxifen
10540-29-1 Basic informationMore
- Product Name:Tamoxifen
- Synonyms: (Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene, trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine 2-[4-[(Z)-1,2-Di(phenyl)but-1-enyl]phenoxy]-N,N-dimethylethanamine 2-[4-[(Z)-1,2-Diphenyl-1-butenyl]phenoxy]-N,N-dimethylethanamine 2-[p-[(Z)-1,2-Diphenyl-1-butenyl]phenyloxy]-N,N-dimethylethanamine N,N-Dimethyl-2-[p-[(Z)-1,2-diphenyl-1-butenyl]phenoxy]ethanamine C07108 Tamoxifen,(Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene, trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine 1-p-β-DiMethylaMinoethoxyphenyl-trans-1,2-diphenylbut-1-ene
- CAS:10540-29-1
- MF:C26H29NO
- MW:371.51
- EINECS:234-118-0
- Mol File:10540-29-1.mol
USE
Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen
(4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF
production in breast tumor cells.
Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response mo
difiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Lastest Price from Tamoxifen manufacturers
- Tamoxifen
- US $610.00 /Kg/Bag
- CAS:10540-29-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 1T
- 2025-01-02
- Tamoxifen
- US $0.00 /kg
- CAS:10540-29-1
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000
- 2024-12-17
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- Company Name:Suzhou Unite pharmTech Co., Ltd ,
- Tel:792-3901125 13222993784
- Products Intro:Product Name:Tamoxifen
CAS:10540-29-1
Purity:99% HPLC Package:25k,5KG;1KG More... - CB Index:56
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- Company Name:Chembest Research Laboratories Limited
- Tel:+86-21-20908456
- Products Intro:Product Name:Tamoxifen(ICI46,474)
CAS:10540-29-1
Purity:99%+ Package:1g;5g;10g;50g;100g;500g;1kg Remarks:C14214 More... - CB Index:61
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- Company Name:Energy Chemical
- Tel:021-021-58432009 400-005-6266
- Products Intro:Product Name:Tamoxifen
CAS:10540-29-1
Purity:98% Package:1g;5g Remarks:NULL More... - CB Index:61
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- Company Name:Adamas Reagent, Ltd.
- Tel:400-6009262 16621234537
- Products Intro:Product Name:Tamoxifen
CAS:10540-29-1
Purity:对照品 Package:10mg~500mg Remarks:AC00011900 More... - CB Index:59
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