Sorafenib tosylate
475207-59-1 Basic informationMore
- Product Name:Sorafenib tosylate
- Synonyms: SORAFENIB TOSYLATE Sorafenib & its intermediates Sorafinib mesylate 4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide monomethanesulfonate Sorafenib Tosylate(Bay 43-9006,Nexavar) 2-PyridinecarboxaMide, 4-[4-[[[[4-chloro-3-(trifluoroMethyl)phenyl]aMino]carbonyl]aMino]phenoxy]-N-Methyl-, 4-Methylbenzenesulfonate Sorafenib Tosylate (Nexavar) Sorafenib (Nexavar)
- CAS:475207-59-1
- MF:C21H16ClF3N4O3.C7H8O3S
- MW:637.03
- EINECS:641-758-8
- Mol File:475207-59-1.mol
USE
In a stage three randomized clinical study of American and European treatments for advanced kidney cancer, 903 cases advanced kidney patients who had experienced one unsuccessful systematic treatment (biological immunity or chemotherapy) were randomly split into two groups. One group received sorafenib tosylate, while the other received a placebo. Mid-term analysis found already 222 deaths and the objective efficacy of the two groups to be 10% and 2%, while 74% and 53% of patients had stabilized conditions. The sorafenib tosylate group’s survival period was longer than that of the placebo group, with the risk ratio as 0.72. However, this different does not have statistical significance, as this is only a mid-term analysis, and final analysis after treatment will yield the correct survival period comparison.<br />
602 advanced liver cancer patients selected from the USA, Europe, Australia, and other countries and areas, who did not receive systematic treatment, were included in a study. Results showed that compared to the placebo, taking sorafenib tosylate could extend their total survival period of patients with late stage or primary liver cancer by about 44% and their extend disease progression period by about 73%.
Lastest Price from Sorafenib tosylate manufacturers
- Sorafenib Tosylate
- US $150.00 /kg
- CAS:475207-59-1
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 500kg
- 2024-12-18
- Sorafenib tosylate
- US $0.00-0.00/Kg/Drum
- CAS:475207-59-1
- Min. Order: 1KG
- Purity: 99%min
- Supply Ability: 500KGS
- 2024-12-13
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- Company Name:Lianyungang Shenghe Biotechnology Co., Ltd.
- Tel:0518-87108777 13585296001
- Products Intro:Product Name:Sorafenib tosylate
CAS:475207-59-1
Purity:99% HPLC Package:25KG;1KG - CB Index:58
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- Company Name:Guangzhou Isun Pharmaceutical Co., Ltd
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- Products Intro:Product Name:Sorafenib tosylate
CAS:475207-59-1
Purity:98% Package:1G; 5G; 25G; 100G; 1KG; 5KG More... - CB Index:55
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- Company Name:Yangzhou QinYuan Pharmaceutical Co., Ltd.
- Tel:0514-80939770 13773367191
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CAS:475207-59-1
Purity:99.9 Package:10000g More... - CB Index:55
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- Company Name:Beijing Jianuode Pharmaceutical Technology Co., Ltd.
- Tel:010-67267894 18611880885
- Products Intro:Product Name:Sorafenib tosylate
CAS:475207-59-1
Purity:99% Package:25kg - CB Index:58
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- Company Name:Shandong Loncom Pharmaceutical Co., Ltd.
- Tel:0531-88072380 0531-88116830 13791093792
- Products Intro:Product Name:Sorafenib tosylate
Purity:99% HPLC Package:1KG,2KG,5KG - CB Index:58
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- Company Name:Shandong Shenghe Pharmaceutical Technology Co. LTD
- Tel: 13585296001
- Products Intro:Product Name:Sorafenib tosylate
CAS:475207-59-1
Purity:99% HPLC Package:25KG;1KG - CB Index:58
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- Company Name:Hubei widely chemical technology Co., Ltd.
- Tel:027-83989310 18627915365
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CAS:475207-59-1
Purity:99% Package:10g;100g;25000g - CB Index:58
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- Company Name:Shan Dong FengJin Pharmaceutical Co.,Ltd.
- Tel: 15898960030
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CAS:857890-39-2
Purity:99.99% Package:10g、kg;50g、kg;100g、kg - CB Index:58
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