MK-1775

• Product Name:MK-1775
• Synonyms: 2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one MK-1775 MK-1775,MK1775 2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1,2-dihydropyrazolo[3,4-d]pyrimidin-3-one 2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one MK 1775 MK 1775 2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one MK-1775, >=98% MK-1175
• CAS:955365-80-7
• MF:C27H32N8O2
• MW:500.6
• EINECS:
• Mol File:955365-80-7.mol
• 

MK-1775 is a small molecule inhibitor of the tyrosine kinase WEE1 with potential antineoplastic sensitizing activity. MK-1775 selectively targets and inhibits WEE1, a tyrosine kinase that phosphorylates cyclin-dependent kinase 1 (CDK1, CDC2) to inactivate the CDC2/cyclin B complex. Inhibition of WEE1 activity prevents the phosphorylation of CDC2 and impairs the G2 DNA damage checkpoint. This may lead to apoptosis upon treatment with DNA damaging chemotherapeutic agents. MK-1775 is a type of biological therapy. It is a cancer growth blocker. It stops signals that cancer cells use to divide and grow. MK-1775 has been used in trials studying the treatment of LYMPHOMA, Neoplasms, Ovarian Cancer, Tongue Carcinoma, and Adult Glioblastoma, among others.

• MK-1775
• 
• US $0.00 /KG
• CAS:955365-80-7
• Min. Order: 1KG
• Purity: 98.1%
• Supply Ability: 100 tons
• 2022-01-14

• Adavosertib
• 
• US $1.50 /g
• CAS:955365-80-7
• Min. Order: 100g
• Purity: 99%
• Supply Ability: 500ton/Month
• 2021-11-15

• Company Name:Wuhan Augda Biotechnology Co., Ltd
• Tel: 15071299552
• Products Intro:Product Name:AZD1775
  CAS:955365-80-7
  Purity:98% Package:mg；g；kg Remarks:mg;g;kg
• CB Index:58
• Related Information:Catalog(6887)

• Company Name:Wuhan Topule
• Tel:+86-02787215551 +86-19945035818
• Products Intro:Product Name:Adavosertib
  CAS:955365-80-7
  Purity:98% hplc lcms Package:5MG;10MG;50MG;100MG,1G,5G， 5KG;1KG
• CB Index:58
• Related Information:Catalog(8084)

• Company Name:Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.
• Tel:+86-027-59232304 15387063101
• Products Intro:Product Name:Adavosertib
  CAS:955365-80-7
  Purity:98% Package:1KG；100g;1g,100mg
• CB Index:58
• Related Information:Catalog(9959)

• Company Name:Shanghai Star Pharmaceutical Chemical Technology Co., Ltd.
• Tel:021-58521787 17701827760
• Products Intro:Product Name:MK-1755
  CAS:955365-80-7
  Purity:98% HPLC Package:100mg, 1g, 10g 现货
• CB Index:58
• Related Information:Catalog(208)

• Company Name:SuZhou GoodChemTech Co., Ltd
• Tel: 18136139868
• Products Intro:Product Name:Adavosertib
  CAS:955365-80-7
  Purity:98% Remarks:10g
• CB Index:58
• Related Information:Catalog(238)

• Company Name:Chembest Research Laboratories Limited
• Tel:+86-21-20908456
• Products Intro:Product Name:2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one
  CAS:955365-80-7
  Purity:98%+ HPLC Package:50mg;100mg;500mg;1g;5g;10g Remarks:Biochemical Reagents; Pharmaceutical Intermediates More...
• CB Index:61
• Related Information:Catalog(6005)