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Tazobactam acid

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Tazobactam is a penicillanic acid sulfone that is similar instructure to sulbactam. It is a more potent β-lactamaseinhibitor than sulbactam and has a slightly broader spectrumof activity than clavulanic acid. It has very weak antibacterialactivity. Tazobactam is available in fixed-dose, injectablecombinations with piperacillin, a broad-spectrum penicillinconsisting of an 8:1 ratio of piperacillin sodium to tazobactamsodium by weight and marketed under the trade name Zosyn.The pharmacokinetics of the two drugs are very similar. Bothhave short half-lives (t<sub>1/2</sub> ~1 hour), are minimally proteinbound, experience very little metabolism, and are excreted inactive forms in the urine in high concentrations.<br>Approved indications for the piperacillin–tazobactamcombination include the treatment of appendicitis, postpartumendometritis, and pelvic inflammatory disease caused byβ-lactamase–producing E. coli and Bacteroides spp., skin andskin structure infections caused by β-lactamase–producingS. aureus, and pneumonia caused by β-lactamase–producingstrains of H. influenzae.
Lastest Price from Tazobactam acid manufacturers
  • Tazobactam
  • US $0.00 /kg
  • CAS:89786-04-9
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 100 tons
  • 2024-02-27
  • Tazobactam acid
  • US $1.00-1.00/KG
  • CAS:89786-04-9
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 50tons
  • 2024-02-01

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