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Maraviroc

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Overall, maraviroc was well tolerated with the most common adverse events being cough, fever, colds, rash, muscle and joint pain, stomach pain, and dizziness. While some patients did experience liver enzyme elevation, these events did not appear to be doserelated. Since hepatotoxicity did occur in one patient with prior liver function abnormalities, maraviroc s label warns of a potentially increased risk of hepatoxicity with treatment. Postural hypotension was also observed in a dosedependent manner; however, no patients discontinued therapy as a result. As a substrate for CYP3A4, the dose of maraviroc should be reduced by 50% in the presence of strong CYP3A4 inhibitors. Conversely, concomitant use of strong CYP3A4 inducers requires a 50% increase in maraviroc dose. While there are no contraindications, maraviroc should be used with caution in patients with liver dysfunction, high risk of cardiovascular events, and pre-existing postural hypotension.
Lastest Price from Maraviroc manufacturers
  • Maraviroc
  • US $10.00 /KG
  • CAS:376348-65-1
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 mt
  • 2024-11-06
  • Maraviroc
  • US $40.00 /kg
  • CAS:376348-65-1
  • Min. Order: 1kg
  • Purity: 0.99
  • Supply Ability: 10 tons
  • 2024-10-25

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