Maraviroc
376348-65-1 Basic informationMore
- Product Name:Maraviroc
- Synonyms: Maraviroc Maraviroc(UK427857) 4,4-Difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide maroviroc 4,4-Difluoro-N-{(1S)-3-[3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl}cyclohexanecarboxamide Maraviroc(Selzentry) 4,4-difluoro-N-[(1S)-3-[(1R,3R,5S)-3-[3-Methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxaMide Celsentri
- CAS:376348-65-1
- MF:C29H41F2N5O
- MW:513.68
- EINECS:609-456-0
- Mol File:376348-65-1.mol
USE
Overall, maraviroc was well tolerated with the most common adverse events being cough, fever, colds, rash, muscle and joint pain, stomach pain, and dizziness. While some patients did experience liver enzyme elevation, these events did not appear to be doserelated. Since hepatotoxicity did occur in one patient with prior liver function abnormalities, maraviroc s label warns of a potentially increased risk of hepatoxicity with treatment. Postural hypotension was also observed in a dosedependent manner; however, no patients discontinued therapy as a result. As a substrate for CYP3A4, the dose of maraviroc should be reduced by 50% in the presence of strong CYP3A4 inhibitors. Conversely, concomitant use of strong CYP3A4 inducers requires a 50% increase in maraviroc dose. While there are no contraindications, maraviroc should be used with caution in patients with liver dysfunction, high risk of cardiovascular events, and pre-existing postural hypotension.
Lastest Price from Maraviroc manufacturers
- Maraviroc
- US $10.00 /KG
- CAS:376348-65-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
- 2024-11-06
- Maraviroc
- US $40.00 /kg
- CAS:376348-65-1
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 10 tons
- 2024-10-25
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- Company Name:Shanghai Yudiao Chemistry Technology Co.,Ltd
- Tel:21-37285211 18964703211
- Products Intro:Product Name:Maraviroc
CAS:376348-65-1
Purity:99.5% HPLC Package:1g/5g/10g/100g/500g/10kg/100-1000kg More... - CB Index:58
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- Company Name:NingBo Sialon Chem Co., Ltd.
- Tel:0574-28809768 18658497215
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CAS:376348-65-1
Purity:99%+ Package:1克/RMB 4500 More... - CB Index:58
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
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CAS:376348-65-1
Package:10Mg,50Mg More... - CB Index:76
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- Company Name:Chemvon Biotechnology Co., Ltd
- Tel:021-50790412
- Products Intro:Product Name:Maraviroc
CAS:376348-65-1
Purity:98% Package:1g, 10g, 100g, 200g, 1kg, 5kg More... - CB Index:57
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:Maraviroc;4,4-Difluoro-N-{(1S)-3-[3-(3-isopropyl-5-Methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl}cyclohexanecarboxaMide
CAS:376348-65-1
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
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- Company Name:Chembest Research Laboratories Limited
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- Products Intro:Product Name:Maraviroc(UK-427857)
CAS:376348-65-1
Remarks:C13855 More... - CB Index:61
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