Verteporfin

• Product Name:Verteporfin
• Synonyms: Verteporfin(DB00460) Verteprofin Verteporfin Verteporphin 24H,26H-Benzo[b]porphine-9,13-dipropanoic acid, 18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-, monomethyl ester, (4R,4aS)-rel- VERTEPIRFIN 9-methyl (I)13-methyl (II)trans-(±)- 18-ethenyl- 4,4a-dihydro-3,4 -bis(methoxycarbonyl)- 4a,8,14,19-tetramethyl- 23H,25H-benzo[b]porphine- 9,13- dipropanoate (4R,4aS)-rel-18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoic acid monomethyl ester
• CAS:129497-78-5
• MF:2C41H42N4O8
• MW:1437.61
• EINECS:
• Mol File:129497-78-5.mol
• 

Verteporfin was introduced in Switzerland as a second-generation photosensitizer for photodynamic therapy of wet age-related macular degeneration in patients with subfoveal choroidal neovascularisation. It is constituted of a mixture of two regioisomers resulting from nonselective monohydrolysis of the methyl tetraester. Upon irradiation with a lowenergy nonheat-generating laser light of 689nm wavelength, both regioisomeric benzoporphyrins are responsible for the local generation of singlet oxygen leading to free radical damage of neovascular endothelial cells in subfoveal lesions of patients with agerelated macular degeneration. The lipophilic drug is injected i.v. as a liposomal formulation in order to favor its uptake by plasma lipoproteins and distribution to cells with a high expression of low density lipoprotein receptors such as tumor and neovascular endothelial cells. Verteporfin is also being developed for the treatment of other eye diseases, nonmelanoma skin cancer and psoriasis.

• Verteporfin
• 
• US $1.10 /g
• CAS:129497-78-5
• Min. Order: 1g
• Purity: 99.0% min
• Supply Ability: 100 tons min
• 2024-04-17

• Company Name:Shanghai Xianhui Pharmaceutical Co., Ltd.
• Tel:13564796979 13564796979
• Products Intro:
• CB Index:62
• Related Information:Catalog(32)

• Company Name:Shanghai Chaolan Chemical Technology Center
• Tel:021-QQ：65489617 15618227136
• Products Intro:Product Name:Verteporfin
  CAS:129497-78-5
  Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G More...
• CB Index:58
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• Company Name:J & K SCIENTIFIC LTD.
• Tel:010-82848833 400-666-7788
• Products Intro:Product Name:Verteporfin
  CAS:129497-78-5
  Package:100Mg,10Mg More...
• CB Index:76
• Related Information:Catalog(96815)

• Company Name:Chembest Research Laboratories Limited
• Tel:+86-21-20908456
• Products Intro:Product Name:Verteporfin
  CAS:129497-78-5
  Purity:98% Package:10mg;50mg;100mg;500mg;1g;5g;10g Remarks:C14327 More...
• CB Index:61
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• Company Name:Adamas Reagent, Ltd.
• Tel:400-6009262 16621234537
• Products Intro:Product Name:Verteporfin
  CAS:129497-78-5
  Purity:95% Package:100mg;250mg;1g
• CB Index:59
• Related Information:Catalog(14103)