Pachymic acid
29070-92-6 Basic informationMore
- Product Name:Pachymic acid
- Synonyms: 3-ACETYLTUMULOSIC ACID PACHYMIC ACID (3b,16a)-3-(Acetyloxy)-16-hydroxy-24-methylenelanost-8-en-21-oic acid 24-methylene-,(3β,16α)- 3-O-Acetyltumulosic acid Lanost-8-en-21-oic acid, 3-(acetyloxy)-16-hydroxy- 3β-Acetyloxy-16α-hydroxy-24-methylenelanost-8-en-21-oic acid Ccris 7792
- CAS:29070-92-6
- MF:C33H52O5
- MW:528.76
- EINECS:
- Mol File:29070-92-6.mol
USE
Pachymic acid (PA) is a natural triterpenoid known to inhibit the phospholipase A2 (PLA(2)) family of arachidonic acid (AA)-producing enzymes, PA-treatment decreases bad phosphorylation, increases Bcl-2 phosphorylation, and activates caspases-9 and -3, it also decreases the expression and activation of proteins within the AKT signal pathway. suggests that PA initiates apoptosis through mitochondria dysfunction and influences apoptosis by reducing prostaglandin.Pachymic acid can exhibit antiinflammatory and anticancer properties, it can inhibit cell growth and modulate arachidonic acid metabolism in nonsmall cell lung cancer A549 cells by its inhibition of MAPKs and NF-kappaB signaling pathways; it can impair breast cancer cell invasion by suppressing nuclear factor-κB-dependent matrix metalloproteinase-9 expression.
Lastest Price from Pachymic acid manufacturers
- Pachymic acid
- US $0.00 /MG
- CAS:29070-92-6
- Min. Order: 20MG
- Purity: ≥98% HPLC
- Supply Ability: 100KG
- 2024-12-24
- Pachymic acid
- US $0.00 /KG
- CAS:29070-92-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100kg
- 2024-11-14
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- Company Name:Jiangxi Baicaoyuan Biotechnology Co. , Ltd.
- Tel:0791-82165230 17707911324
- Products Intro:Product Name:Pachymicacid
CAS:29070-92-6
Purity:98% Package:10mg 20mg 50mg 100mg 1g 等根据客户要求不同规格 - CB Index:58
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- Company Name:Shanghai Standard Technology Co.,Ltd.
- Tel:021-021-57127007-6622-6622 17621252073
- Products Intro:Product Name:Pachymic acid
CAS:29070-92-6
Purity:HPLC>=98% Package:10mg More... - CB Index:58
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- Company Name:Shanghai Winherb Medical Technology Co., Ltd.
- Tel:400-186-5138 13341702378
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CAS:29070-92-6
Purity:HPLC>99% Package:20mg;100mg;1g - CB Index:58
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- Company Name:Chembest Research Laboratories Limited
- Tel:+86-21-20908456
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CAS:29070-92-6
Remarks:C11693 More... - CB Index:61
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- Company Name:Dalian Meilun Biotech Co., Ltd.
- Tel:0411-62910999 13889544652
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CAS:29070-92-6
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- Company Name:BioBioPha Co., Ltd.
- Tel:0871-65217109 13211707573;
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CAS:29070-92-6
Purity:96.0% Package:5mg Remarks:BBP04908 More... - CB Index:65
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- Company Name:ShangHai YuanYe Biotechnology Co., Ltd.
- Tel:021-61312847 13636370518
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CAS:29070-92-6
Purity:HPLC≥97% Package:5mg More... - CB Index:60
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