MONOCROTALINE
315-22-0 Basic informationMore
- Product Name:MONOCROTALINE
- Synonyms: (13-alpha,14-alpha)-14,19-dihydro-12,13-dihydroxy-20-norcrotalanan-11,15-dio (13-alpha,14-alpha)-14,19-Dihydro-12,13-dihydroxy-20-norcrotalanan-11,15-dione (2,3,4-gh)pyrrolizine-2,6(3h)-dione,(4,5,8,10,12,13,13a,13b-octahydro-4,5-dihy (2,3,4-gh)pyrrolizine-2,6(3H)-dione,(4,5,8,10,12,13,13a,13b-octahydro-4,5-dihydroxy-3,4,5-trimethyl-2H-(1,6)dioxacycloundecino- 12-beta,13-beta-dihydroxy-12-alpha,13-alpha,14-alpha-trimethylcrotal-1-enine 12beta,13beta-Dihydroxy-12alpha,13alpha,14alpha-trimethylcrotal-1-enine 14,19-dihydro-12,13-dihydroxy(13-alpha,14-alpha)-20-norcrotalanan-11,15-dione 14,19-Dihydro-12,13-dihydroxy(13alpha,14alpha)-20-norcrotalanan-11,15-dione
- CAS:315-22-0
- MF:C16H23NO6
- MW:325.36
- EINECS:628-506-2
- Mol File:315-22-0.mol
-
USE
Monocrotaline (MCT) is a toxic 11-membered macrocyclic pyrrolizidine alkaloid (PA) derived from the seeds of the Crotalaria spectabilis plant. It poisons livestock and humans through the ingestion of contaminated grains and other foods. Pyrrolizidine alkaloid is activated by cytochrome P450 to the reactive pyrrole metabolite dehydromonocrotaline (MCTP) in the liver. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature.<br />
Monocrotaline is produced for research use. It is used in rat model to investigate human pulmonary hypertension as it offers technical simplicity, reproducibility, and low cost compared with other models of pulmonary hypertension.
Lastest Price from MONOCROTALINE manufacturers
- Monocrotaline
-
- US $0.00 /mg
- CAS:315-22-0
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- 2023-02-24
- MONOCROTALINE
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- US $1.10 /g
- CAS:315-22-0
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
- 2021-07-03
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- Company Name:Nanjing Bencao Yikang Biotechnology Co., Ltd
- Tel:+86-025-69790911 18362932668
- Products Intro:Product Name:Crotaline
CAS:315-22-0
Purity:98% HPLC Package:根据客户需求包装 - CB Index:58
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- Company Name:Chengdu Peter-like Biotechnology Co., Ltd.
- Tel:028-81700200 18108052721
- Products Intro:Product Name:Crotaline
CAS:315-22-0
Purity:HPLC>=98% Package:5mg;10mg;20mg;50mg;100mg;200mg More... - CB Index:58
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Crotaline, 98%, from Lilium brownii F.E.Br. ex Miellez
CAS:315-22-0
Purity:98% Package:10MG More... - CB Index:76
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- Company Name:Chembest Research Laboratories Limited
- Tel:021-20908456
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CAS:315-22-0
Purity:98% Package:10g Remarks:C11518 More... - CB Index:61
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- Company Name:BEST-REAGENT
- Tel:400-1166-196 18981987031
- Products Intro:Product Name:MONOCROTALINE
CAS:315-22-0
Purity:99% HPLC Package:10g;50g;100g;500g;1kg;5kg;25kg More... - CB Index:57
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- Company Name:Hunan Hui Bai Shi Biotechnology Co., Ltd.
- Tel:0731-85526065 13308475853
- Products Intro:Product Name:MONOCROTALINE
CAS:315-22-0
Purity:98% HPLC Package:1g;5g；500g More... - CB Index:62
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