LEE011

• Product Name:LEE011
• Synonyms: LEE011 CDK4/6 inhibitor CDK4 inhibitor CDK4-IN-1 CDK 4/6 Inhibitor, >=98% Ribociclib(Lee011 & CDK 4/6 inhibitor) 4-[5-Chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-[5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl]-2-pyrimidinamine 4-(3-chloro-5-propan-2-yl-1H-pyrazol-4-yl)-N-[5-[4-(dimethylamino)piperidin-1-yl]pyridin-2-yl]pyrimidin-2-amine
• CAS:1256963-02-6
• MF:C22H29ClN8
• MW:440.97
• EINECS:
• Mol File:1256963-02-6.mol
• 

LEE011 (also known as ribociclib) is a CDK4/6 inhibitor. It has been recently approved by FDA (brand name: Kisqali®) to be combined with an aromatase inhibitor for initial endocrine-based therapy for treatment of postmenopausal women with hormone receptor positive, human epidermal growth factor receptor-2 negative (HR+/HER2-) advanced or metastatic breast cancer. It inhibits the growth of tumor cells by arresting the cells at the G1 checkpoint, which prevents the tumor cells from proliferating. In the phase III trial, it demonstrating statistically significant improvement in progression-free survival (PFS) compared to letrozole alone at the first pre-planned interim analysis. 

• Ribociclib
• 
• US $0.00 /g
• CAS:1256963-02-6
• Min. Order: 1g
• Purity: 98% HPLC
• Supply Ability: 1kg
• 2024-11-19

• LEE011
• 
• US $1.10 /g
• CAS:1256963-02-6
• Min. Order: 1g
• Purity: 99.9%
• Supply Ability: 100 Tons Min
• 2021-07-02

• Company Name:Shenzhen Yaoyuan R&D Center Co., Ltd
• Tel:13421666688 13421666688
• Products Intro:Product Name:Ribociclib
  CAS:1256963-02-6
  Purity:99% Package:1KG/RMB 10;5KG10KG
• CB Index:58
• Related Information:Catalog(410)

• Company Name:J & K SCIENTIFIC LTD.
• Tel:010-82848833 400-666-7788
• Products Intro:Product Name:CDK 4/6 Inhibitor
  CAS:1256963-02-6
  Package:2.5Mg,25Mg More...
• CB Index:76
• Related Information:Catalog(96815)