Sulindac

• Product Name:Sulindac
• Synonyms: Sulindac Solution, 100ppm Sulindac SynonyMs (Z)-5-Fluoro-2-Methyl-1-[p-(Methylsulfinyl)benzylidene]indene-3-acetic acid 1h-indene-3-aceticacid,5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methyle Aclin arthrocine (z)-5-fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1h-indene-3-ac sulindacsulfoxide (Z)-5-FLUORO-2-METHYL-1-[P-(METHYLSULFINYL)BENZYLIDENE]INDENE-3-ACETIC ACID
• CAS:38194-50-2
• MF:C20H17FO3S
• MW:356.41
• EINECS:253-819-2
• Mol File:38194-50-2.mol
• 

Sulindac, (Z)-5-fluoro-2-methyl-1-([p-(methylsulfinyl)phenyl]methylene)-1H-indene-3-acetic acid (Clinoril), isan NSAID prodrug that contains a chiral sulfoxide moietybut is marketed as the racemate because it undergoes invivo reduction by the hepatic enzymes into its achiral, activemetabolite, methyl sulfide that exhibits potent andnonselective COX inhibition similar to indomethacin.<br/>The parent sulfoxide has a plasma half-life of 8 hours, andthe active methyl sulfide metabolite is 16.4 hours. The morepolar and inactive sulfoxide is virtually the only form excretedinto the renal tubules, thus sulindac is believed to haveminimal nephrotoxicity associated with indomethacin. Thelong half-life of sulindac is caused by the extensive enterohepaticcirculation and reactivation of the inactive sulfoxideexcreted. Coadministration of aspirin is contraindicated becauseit considerably reduces the sulfide blood levels. Carefulmonitoring of patients with a history of ulcers is recommended.Gastric bleeding, nausea, diarrhea, dizziness, andother adverse effects have been noted with sulindac, but witha lower frequency than with aspirin. Sulindac is recommendedfor RA, OA, and ankylosing spondylitis.

• Sulindac
• 
• US $60.00 /kg
• CAS:38194-50-2
• Min. Order: 1kg
• Purity: 99%
• Supply Ability: 20 tons
• 2024-11-28

• Sulindac
• 
• US $0.00 /Kg/Bag
• CAS:38194-50-2
• Min. Order: 1KG
• Purity: 99%-101%;USP/BP
• Supply Ability: 500KG
• 2024-11-27

• Company Name:Tai Zhou World Pharm & Chem Co., Ltd
• Tel:0576-85301198 13736201658
• Products Intro:Product Name:Sulindac
  CAS:38194-50-2
  Purity:99% HPLC Package:25KG;5KG;1KG;500kg;100kg
• CB Index:58
• Related Information:Catalog(104)

• Company Name:Wuhan Fortuna Chemical Co., Ltd
• Tel:027-59207852 13308628970
• Products Intro:Product Name:Sulindac
  CAS:38194-50-2
  Purity:99% Package:1kg,25kg More...
• CB Index:58
• Related Information:Catalog(2871)

• Company Name:Hangzhou Xiao Bei Medical Technology Co., LTD
• Tel:571-8526-3177 13962438025
• Products Intro:Product Name:Sulindac
  CAS:38194-50-2
  Purity:99 Package:500G;1KG;25KG Remarks:kg
• CB Index:58
• Related Information:Catalog(164)

• Company Name:J & K SCIENTIFIC LTD.
• Tel:010-82848833 400-666-7788
• Products Intro:Product Name:Sulindac, 98%, a COX inhibitor
  CAS:38194-50-2
  Purity:98% Package:1G;250MG;50G;5G More...
• CB Index:76
• Related Information:Catalog(96815)

• Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
• Tel:821-50328103-801 18930552037
• Products Intro:Product Name:Sulindac;(1Z)-5-Fluoro-2-Methyl-1-[[4-(Methylsulfinyl)phenyl]Methylene]-1H-indene-3-aceticacid
  CAS:38194-50-2
  Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More...
• CB Index:69
• Related Information:Catalog(15839)

• Company Name:Chembest Research Laboratories Limited
• Tel:+86-21-20908456
• Products Intro:Product Name:Sulindac
  CAS:38194-50-2
  Remarks:C14198 More...
• CB Index:61
• Related Information:Catalog(6005)

• Company Name:Energy Chemical
• Tel:021-021-58432009 400-005-6266
• Products Intro:Product Name:Sulindac
  CAS:38194-50-2
  Purity:98% Package:1g;5g;25g;100g;10g;50g;50mg Remarks:NULL More...
• CB Index:61
• Related Information:Catalog(44688)