Clopidogrel

• Product Name:Clopidogrel
• Synonyms: CLOPIDOGREL ClopidogrelHydrobromide ClopidogrelHydrogenSulfateBase ClopidogrelHcl Methyl (+)-(S)-α-(o-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate (S)- α-(2-Chlorophenyl)-6，7-dihydrothieno[3，2-c]pyridine-5(4H)-acetic acidmethyl ester Clopidogrel Pellets Methyl (2S)-2-(2-chlorophenyl)-2-{4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl}acetate
• CAS:113665-84-2
• MF:C16H16ClNO2S
• MW:321.82
• EINECS:601-269-2
• Mol File:113665-84-2.mol
• 

Clopidogrel was launched in the US as a potent inhibitor of platelet aggregation for the preventive management of secondary ischemic events, including MI, stroke and vascular deaths. Clopidogrel can be synthesized in 4 steps (including an optical resolution to the S active enantiomer) from 2-(2- ch1orophenyl)-glycine, the key step being the cyclization to thienopyridine with formaldehyde and acetic acid. Clopidogrel belongs to the original chemical class of Ticlopidine, but shows fewer side effects (in particular, bone-marrowsuppressing effects) at the dosage generally used. Like Ticlopidine, it is an Adenosine diphosphate (ADP) antagonist acting at the purinergic P2y receptor. In in vivo experiments with rabbits, Clopidogrel shows a maximal antiaggregant effect at 20mg/kg po, reducing adhesion of platelets to the vascular subendothelium ; moreover, it reduces myointimal thickening occuring after endothelial injury of rat carotid artery. Clopigrel does not affect platelet aggregation in vitro ; actually, its in vivo activity is highly dependent on hepatic metabolism. The results of a CAPRIE trial (Clopidogrel versus Aspirin in patients at risk of ischemic events) demonstrated that Clopidogrel was well tolerated and more effective than aspirin.

• Clopidogrel
• 
• US $0.00-0.00/Kg
• CAS:113665-84-2
• Min. Order: 1Kg
• Purity: 99.9%
• Supply Ability: 200tons
• 2024-04-09

• Clopidogrel
• 
• US $0.00-0.00/Kg/Drum
• CAS:113665-84-2
• Min. Order: 1KG
• Purity: 98%min
• Supply Ability: 1000kg
• 2023-11-15

• Company Name:Sichuan Ruibo Technology Co., Ltd
• Tel:+86-817-5586080
• Products Intro:Purity:97.8%
• CB Index:69
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• Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
• Tel:821-50328103-801 18930552037
• Products Intro:Product Name:Clopidogrel
  CAS:113665-84-2
  Purity:98% HPLC Package:1g;5g;25g;100g More...
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• Company Name:Chembest Research Laboratories Limited
• Tel:021-20908456
• Products Intro:Product Name:Clopidogrel
  CAS:113665-84-2
  Remarks:C14435 More...
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• Company Name:Shanghai Longsheng chemical Co.,Ltd.
• Tel:021-58099652-8005 13585536065
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  CAS:113665-84-2
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• Company Name:Shanghai Hanhong Scientific Co.,Ltd.
• Tel:021-54306202 13764082696;
• Products Intro:Product Name:Clopidogrel
  CAS:113665-84-2
  Purity:98+% Remarks:AB00531 More...
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