KL001
309928-48-1 Basic informationMore
- Product Name:KL001
- Synonyms: N-[3-(9H-Carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)-methanesulfonamide N-(3-(9H-Carbazol-9-yl)-2-hydroxypropyl)-N-(furan-2-ylmethyl)methanesulfonamide Methanesulfonamide, N-[3-(9H-carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)- KL001(KL-001 Inhibitor,inhibit,stabilizer,KL001,circadian,cryptochrome,ubiquitin,period,gluconeogenesis,CRY
- CAS:309928-48-1
- MF:C21H22N2O4S
- MW:398.48
- EINECS:
- Mol File:309928-48-1.mol
-
USE
KL001 is a small molecule that specifically interacts with cryptochrome (CRY). KL001 prevented ubiquitin-dependent degrdation of CRY, resulting in lengthening of the circadian period. KL001-mediated CRY stabilization inhibited glucagon-induced gluconeogenesis in primary hepatocytes making it a tool to study the regulation of CRY-dependent physiology and aid development of clock-based therapeutics of diabetes.
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:KL001
CAS:309928-48-1
Package:10Mg,50Mg,5Mg More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:Sigma-Aldrich
- Tel:021-61415566 800-8193336
- Products Intro:Product Name:KL001
CAS:309928-48-1
Purity:>=98% (HPLC) Package:25MG Remarks:SML1032-25MG - CB Index:80
- Related Information:Catalog(51471)
- Company Name:Shanghai Lollane Biological Technology Co.,Ltd.
- Tel:021-52996696，15000506266 15000506266
- Products Intro:Product Name:KL001
CAS:309928-48-1
Purity:98% HPLC Package:5mg，10mg，50mg，100mg，1g，5g - CB Index:55
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- Company Name:Shanghai EFE Biological Technology Co., Ltd.
- Tel:021-65675885 18964387627
- Products Intro:Product Name:KL001
CAS:309928-48-1
Purity:98.00% Package:1mg;5mg;10mg - CB Index:58
- Related Information:Catalog(9806)
- Company Name:ShangHai Biochempartner Co.,Ltd
- Tel:17754423994 17754423994
- Products Intro:Product Name:KL001
CAS:309928-48-1
Purity:98% HPLC LCMS Package:100MG;1G - CB Index:62
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- Company Name:Shanghai Rechem science Co., Ltd.
- Tel:21-31433387 15618786686
- Products Intro:CAS:309928-48-1
Purity:98% Package:1g/ - CB Index:58
- Related Information:Catalog(2990)
- Company Name:Shanghai Chaolan Chemical Technology Center
- Tel:QQ:65489617 15618227136
- Products Intro:Product Name:KL001
CAS:309928-48-1
Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G - CB Index:58
- Related Information:Catalog(9946)