Ceftriaxone sodium
74578-69-1 Basic informationMore
- Product Name:Ceftriaxone sodium
- Synonyms: CEFATRIAXONE 2,5,6-tetrahydro-2-methyl-5,6-dioxo-)(methoxyimino)acetyl)amino)-8-oxo-3-((( 4-triazin-3-yl)thio)methyl)-,sodiumsalt,hydrate(2:4:7)(6r-(6-alpha,7-2 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, disodium salt, [6R-[6α,7β(Z)]]- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, disodium salt, (6R,7R)- [6R-[6alpha,7beta(Z)]]-7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt Ceftriaxone sodium Ceferiaxone SodiuM Sterile
- CAS:74578-69-1
- MF:C18H19N8NaO7S3
- MW:578.57
- EINECS:277-930-0
- Mol File:74578-69-1.mol
USE
<p>Ceftriaxone sodium is antibacteria.</p>
<p>Ceftriaxone sodium is a β-lactamase–resistantcephalosporin with an extremely long serum half-life.Once-daily dosing suffices for most indications. Two factorscontribute to the prolonged duration of action ofceftriaxone: high protein binding in the plasma and slowurinary excretion. Ceftriaxone is excreted in both the bileand the urine. Its urinary excretion is not affected byprobenecid. Despite its comparatively low volume ofdistribution, it reaches the cerebrospinal fluid in concentrationsthat are effective in meningitis. Nonlinear pharmacokineticsare observed.<br>
Ceftriaxone contains a highly acidic heterocyclic systemon the 3-thiomethyl group. This unusual dioxotriazine ringsystem is believed to confer the unique pharmacokineticproperties of this agent. Ceftriaxone has been associatedwith sonographically detected “sludge,” or pseudolithiasis,in the gallbladder and common bile duct. Symptoms ofcholecystitis may occur in susceptible patients, especiallythose on prolonged or high-dose ceftriaxone therapy. Theculprit has been identified as the calcium chelate.<br>
Ceftriaxone exhibits excellent broad-spectrum antibacterialactivity against both Gram-positive and Gram-negativeorganisms. It is highly resistant to most chromosomally andplasmid-mediated β-lactamases. The activity of ceftriaxoneagainst Enterobacter, Citrobacter, Serratia, indole-positiveProteus, and Pseudomonas spp. is particularly impressive. Itis also effective in the treatment of ampicillin-resistant gonorrheaand H. influenzae infections but generally less activethan cefotaxime against Gram-positive bacteria and B.fragilis.</p>
Lastest Price from Ceftriaxone sodium manufacturers
- Ceftriaxone Sodium
- US $150.00 /kg
- CAS:74578-69-1
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 500kg
- 2024-12-20
- Ceftriaxone sodium
- US $0.00 /KG/Tin
- CAS:74578-69-1
- Min. Order: 1KG
- Purity: ≥795 μg/mg;Sterile; USP
- Supply Ability: 1000kg
- 2024-12-13
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- Company Name:Hubei widely chemical technology Co., Ltd.
- Tel:027-83991130 18627774460
- Products Intro:Product Name:Ceftriaxone sodium
CAS:74578-69-1
Purity:0.98 Package:8KG More... - CB Index:58
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- Company Name:Jinan Yunding Biotechnology Co., Ltd
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Purity:99.99% Package:1kg/RMB 100 - CB Index:58
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- Company Name:Hunan Revel Biotechnology Co. , Ltd.
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CAS:74578-69-1
Purity:98% HPLC Package:1KG;5KG;10KG;100KG - CB Index:58
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- Company Name:XiaoGan ShenYuan ChemPharm co,ltd
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Purity:98% Package:10 Remarks:10KG More... - CB Index:52
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CAS:74578-69-1
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- Company Name:S.Z. PhyStandard Bio-Tech. Co., Ltd.
- Tel:0755-4000505016 13380397412
- Products Intro:Product Name:Ceftriaxone sodium
CAS:74578-69-1
Purity:99% HPLC Package:10mg;25mg;50mg;100mg - CB Index:50
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