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CAY10412

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USE
Anandamide (arachidonoyl ethanolamide; AEA) is an endogenous lipid with cannabinergic activity; along with 2-arachidonoyl glycerol, it forms part of the endocannabinoid system. AEA undergoes reuptake into neurons by a facilitated process. Controversy exists as to whether there is a specific AEA transporter, or instead the uptake process is simply driven by hydrolysis of AEA by intracellular fatty acyl amide hydrolase (FAAH). CAY10412 is an analog of AEA that has no intrinsic binding affinity for either CB1 or CB2 receptors. It is a potent inhibitor of AEA reuptake in U937 lymphoma cells, with an IC50 of 3 μM. CAY10412 could be a useful tool for distinguishing the competing transporter theories. The pharmacology of CAY10412 is largely unexplored; it may enhance endocannabinoid signalling by augmenting endocannabinoid concentrations.

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  • Company Name:ChemeGen(Shanghai) Biotechnology Co.,Ltd.
  • Tel: 18818260767
  • Products Intro:Product Name:CAY10412
    CAS:390824-17-6
    Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
  • CB Index:58
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  • Company Name:TargetMol Chemicals Inc.
  • Tel: 4008200310
  • Products Intro:Product Name:CAY10412
    CAS:390824-17-6
    Package:5mg/RMB 665;10mg/RMB 1240;50mg/RMB 4970
  • CB Index:58
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  • Company Name:Shanghai Hao Zhun Biological Technology Co., Ltd.
  • Tel: 15800340161
  • Products Intro:Product Name:CAY10412
    CAS:390824-17-6
    Purity:98%
  • CB Index:58
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  • Company Name:Shanghai Haoran Biotechnology Co., Ltd.
  • Tel:021-54046791
  • Products Intro:Product Name:CAY10412
    CAS:390824-17-6
  • CB Index:58
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  • Company Name:Beijing Bolide Biotechnology Co., Ltd.
  • Tel:010-51653916
  • Products Intro:Product Name:CAY10412
    CAS:390824-17-6
  • CB Index:58
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  • Company Name:Absin Bioscience Inc.
  • Tel:021-38015121
  • Products Intro:Product Name:CAY10412
    CAS:390824-17-6
  • CB Index:58
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  • Company Name:Shanghai Yaoyun Biological Technology Co., Ltd.
  • Tel:400-002-6926 400-002-6926
  • Products Intro:Product Name:CAY10412
    CAS:390824-17-6
  • CB Index:58
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