Plitidepsin
137219-37-5 Basic informationMore
- Product Name:Plitidepsin
- Synonyms: Plitidepsin 2-9-Didemnin B, 2-(1-(1,2-dioxopropyl)-L-proline)- Aplidin Didemnin A, N-(1-(1,2-dioxopropyl)-L-prolyl)- L-Tyrosine, 1-(1,2-dioxopropyl)-L-prolyl-N-methyl-D-leucyl-L-threonyl-(3S,4R,5S)-4-amino-3-hydroxy-5-methylheptanoyl-(2S,4S)-4-hydroxy-2,5-dimethyl-3-oxohexanoyl-L-leucyl-L-prolyl-N,o-dimethyl-, (8-3)-lactone 3,6-Anhydro-(N-{(2S,4S)-4-[(3S,4R,5S)-3-hydroxy-4-{[N-(2-oxo-propanoyl)-L-prolyl-N-Methyl-D-leucyl-L-threonyl]aMino}-5-Methyl-heptanoyloxy]-2,5-diMethyl-3-oxohexanoyl}-L-leucyl-L-prolyl-N cyclic peptide deriv. (2S)-N-[(2R)-1-[[(3S,6S,8S,12S,13R,16S,17R,20S,23S)-13-[(2S)-butan-2-yl]-12-hydroxy-20-[(4-methoxyphenyl)methyl]-6,17,21-trimethyl-3-(2-methylpropyl)-2,5,7,10,15,19,22-heptaoxo-8-propan-2-yl-9,18-dioxa-1,4,14,21-tetrazabicyclo[21.3.0]hexacosan-16-yl]amino]-4-methyl-1-oxopentan-2-yl]-N-methyl-1-(2-oxopropanoyl)pyrrolidine-2-carboxamide
- CAS:137219-37-5
- MF:C57H87N7O15
- MW:1110.34
- EINECS:
- Mol File:137219-37-5.mol
-
USE
Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin displays a broad spectrum of antitumor activities, inducing apoptosis by triggering mitochondrial cytochrome c release, initiating the Fas/ DC95, JNK pathway and activating caspase 3 activation. This agent also inhibits elongation factor 1-a, thereby interfering with protein synthesis, and induces G1 arrest and G2 blockade, thereby inhibiting tumor cell growth.
Lastest Price from Plitidepsin manufacturers
- Plitidepsin
-
- US $8.00-0.80/kg
- CAS:137219-37-5
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- 2024-04-08
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- Company Name:Henan Fengda Chemical Co., Ltd
- Tel:+86-371-86557731
- Products Intro:Product Name: Plitidepsin
CAS:137219-37-5
Purity:99% Package:1kg;8USD|25kg;2USD|100kg;0.8USD - CB Index:58
- Related Information:Catalog(20124)
- Company Name:ATK CHEMICAL COMPANY LIMITED
- Tel:+undefined-21-51877795
- Products Intro:Product Name:Plitidepsin
CAS:137219-37-5
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G - CB Index:60
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- Company Name:SHANGHAI T&W PHARMACEUTICAL CO., LTD.
- Tel:+86-021-61551413
- Products Intro:Product Name:Plitidepsin
CAS:137219-37-5
Purity:98% Package:Package as requetsed - CB Index:58
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- Company Name:Zhejiang Huida Biotech Co., LTD
- Tel:008613515763466
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CAS:137219-37-5
Purity:95%;98% Package:1g;USD - CB Index:58
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- Company Name:AFINE CHEMICALS LIMITED
- Tel:+86-0571-85134551
- Products Intro:Product Name:PLITIDEPSIN
CAS:137219-37-5
Purity:98%+ Package:Standard or custom package Remarks:excellent quality and reliable supplier - CB Index:58
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- Company Name:Henan Alfa Chemical Co., Ltd
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Purity:97% Min. Package:5g; 25g; 100g; 500g; 1kg; 25kg - CB Index:58
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- Company Name:Nextpeptide Inc
- Tel:+86-0571-81612335
- Products Intro:Product Name:Aplidine
CAS:137219-37-5
Purity:98% Min. Package:5KG;1KG - CB Index:58
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- Company Name:Zibo Hangyu Biotechnology Development Co., Ltd
- Tel:+86-0533-2185556
- Products Intro:Product Name:Plitidepsin
CAS:137219-37-5
Purity:99% - CB Index:58
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