Sitagliptin

• Product Name:Sitagliptin
• Synonyms: Sitagliptin (3R)-3-AMino-1-[3-(trifluoroMethyl)-5,6,7,8-tetrahydro-1,2,4-riazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-rifluorophenyl) butan-1-one Sitagliptin-D4 HCL Hsdb 7516 C53323300 Metformin / sitagliptin Metformin hydrochloride mixture with sitagliptin phosphate Metformin mixture with sitagliptin
• CAS:486460-32-6
• MF:C16H15F6N5O
• MW:407.31
• EINECS:690-730-1
• Mol File:486460-32-6.mol
• 

Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, is a first-in-class oral drug launched for the treatment of type 2 diabetes. It acts by slowing the inactivation of incretins, which are endogenous peptides involved in the physiologic regulation of glucose homeostasis. Incretin hormones, including glucagonlike peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), are released by the intestine throughout the day, and levels are increased in response to a meal. When blood glucose concentrations are normal or elevated,GLP-1 and GIP increase the synthesis and release of insulin from pancreatic b cells via intracellular signaling pathways involving cAMP. GLP-1 also lowers glucagon secretion from pancreatic αcells, which leads to reduced hepatic glucose production.

• Sitagliptin
• 
• US $200.00-85.00/Kg/Bag
• CAS:486460-32-6
• Min. Order: 1Kg/Bag
• Purity: 98.5% up
• Supply Ability: 20tons
• 2024-04-10

• Sitagliptin
• 
• US $0.00-0.00/kg
• CAS:486460-32-6
• Min. Order: 0.10000000149011612kg
• Purity: 99
• Supply Ability: 20tons
• 2024-04-07

• Company Name:AnHui HaiKang Pharmaceutical Co., Ltd.
• Tel:0556-5800026 17709662922
• Products Intro:Product Name:Sitagliptin
  CAS:486460-32-6
  Purity:99 Package:25kg/tub Remarks:KG More...
• CB Index:55
• Related Information:Catalog(212)

• Company Name:Suzhou Xinkai Bio-Medical Technology Co., Ltd.
• Tel:0512-67213637 13952409868
• Products Intro:Product Name:(R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one
  CAS:486460-32-6
  Purity:98% Package:50g More...
• CB Index:55
• Related Information:Catalog(452)

• Company Name:Ningbo Zhenlei Chemical Co.,ltd.
• Tel:0576-057688203603 13958565781
• Products Intro:Product Name:Sitagliptin free base
  CAS:486460-32-6
  Purity:99% HPLC Package:25KG;
• CB Index:58
• Related Information:Catalog(84)

• Company Name:Anhui Cheer-Our Medical technology Co.,Ltd
• Tel: 13855402841
• Products Intro:Product Name:Sitagliptin
  CAS:486460-32-6
  Purity:99% Package:25kg
• CB Index:58
• Related Information:Catalog(93)

• Company Name:Tiantai Yisheng Biochemical Technology Co., Ltd
• Tel: 18958639818
• Products Intro:Product Name:Sitagliptin
  CAS:486460-32-6
  Purity:>=99 Package:25kg;50kg;1000kg
• CB Index:58
• Related Information:Catalog(120)

• Company Name:ChemFuture PharmaTech (Jiangsu) Ltd
• Tel:5108538618
• Products Intro:Product Name:Sitagliptin
  CAS:486460-32-6
  More...
• CB Index:65
• Related Information:Catalog(822)

• Company Name:Chembest Research Laboratories Limited
• Tel:021-20908456
• Products Intro:Product Name:Sitagliptin
  CAS:486460-32-6
  Remarks:C14173 More...
• CB Index:61
• Related Information:Catalog(6011)

• Company Name:BeiJing Hwrk Chemicals Limted
• Tel:0757-86329057 18501085097
• Products Intro:Product Name:(R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one
  CAS:486460-32-6
  Purity:97.00% Package:10g Remarks:HWG49425
• CB Index:55
• Related Information:Catalog(7583)