arglabin

• Product Name:arglabin
• Synonyms: (3aR,4aS,6aS,9aS,9bR)-5,6,6a,7,9a,9b-Hexahydro-1,4a-dimethyl-7-methylene-3H-oxireno[8,8a]azuleno[4,5-b]furan-8(4aH)-one arglabin (3aR,4aS)-1,4aα-Dimethyl-7-methylene-4a,5,6,6aα,9aβ,9bα-hexahydro-3H-oxireno[8,8a]azuleno[4,5-b]furan-8(7H)-one (3aS)-2,3,3aβ,4,5β,6,6a,7,9aβ,9bα-Decahydro-6α,6aα-epoxy-6,9-dimethyl-3-methyleneazuleno[4,5-b]furan-2-one 3H-Oxireno[8,8a]azuleno[4,5-b]furan-8(4aH)-one, 5,6,6a,7,9a,9b-hexahydro-1,4a-diMethyl-7-Methylene-, [4aS-(3aS*,4aα,6aα,9aβ,9bα)]- Arglabine 3H-Oxireno[8,8a]azuleno[4,5-b]furan-8(4aH)-one,5,6,6a,7,9a,9b-hexahydro-1,4a-dimethyl-7-methylene-, (3aR,4aS,6aS,9aS,9bR) Arglabin 84692-91-1
• CAS:84692-91-1
• MF:C15H18O3
• MW:246.3
• EINECS:
• Mol File:84692-91-1.mol
• 

Arglabin is a new antineoplastic agent launched in Russia for the treatment of a variety of cancers. It is a sesquiterpene gamma-lactone extracted from Artemisia glabella, a plant from Kazakstan; it was first developed in Kazakstan followed by US and other countries as an ethical pharmaceutical. Arglabin can be obtained by resin extraction from A.glabella, purification by chromatography and finally recrystallization. Arglabin is a potent and selective inhibitor of farnesyl transferase, an enzyme critical to the function of the Ras oncogene in cancer cell reproduction. It showed a strong Inhibitory effect against tumor cells proliferation in in vitro models of transformed mouse hepatocytes and splenocytes. This cytotoxic effect against tumor cells was 50-100 times higher than that on intact cells. In many patients with various cancers, Arglabin was shown to stop or inhibit the tumour development, alone or in combination with other anticancer agents, and was reportedly well tolerated with few sideeffects. Promising response rates were also reported with Arglabin after treating other 《difficult-to-treat cancers》 such as breast, ovarian, lung or colon cancers.

• Arglabin 84692-91-1
• 
• US $130.00 /mg
• CAS:84692-91-1
• Min. Order: 20mg
• Purity: ≥98%
• Supply Ability: 1000.00 kgs
• 2022-07-06

• Company Name:BioBioPha Co., Ltd.
• Tel:0871-65217109 13211707573;
• Products Intro:Product Name:Arglabin
  CAS:84692-91-1
  Purity:98.0% Package:5mg Remarks:BBP04622 More...
• CB Index:65
• Related Information:Catalog(5653)

• Company Name:Chengdu Biopurify Phytochemicals Ltd.
• Tel:+86-028-82633397 18982077548
• Products Intro:Product Name:Arglabin
  CAS:84692-91-1
  Purity:>95%,98%,99% Package:From mgs to grams,up to Kgs.Inquire for Bulk scale. More...
• CB Index:60
• Related Information:Catalog(2376)

• Company Name:Shanghai Winherb Medical Technology Co., Ltd.
• Tel:400-186-5138 13341702378
• Products Intro:Product Name:Arglabine
  CAS:84692-91-1
  Purity:HPLC>98% Package:5mg;20mg;100mg
• CB Index:58
• Related Information:Catalog(1009)

• Company Name:Nanjing Spring & Autumn Biological Engineering Co., Ltd.
• Tel:025-84430028 13815430202
• Products Intro:Product Name:Arglabin
  CAS:84692-91-1
  Purity:HPLC >= 98% Package:g-kg,in stock,customized More...
• CB Index:59
• Related Information:Catalog(282)

• Company Name:Shanghai Tauto Biotech Co., Ltd.
• Tel:021-51320588
• Products Intro:Product Name:Arglabine
  CAS:84692-91-1
  Purity:98% Package:10mg;20mg;1gm;5gm;10gm;1KG
• CB Index:66
• Related Information:Catalog(3989)

• Company Name:Hubei Jusheng Technology Co.,Ltd
• Tel:027-59599241 18871490274
• Products Intro:Product Name:arglabin
  CAS:84692-91-1
  Purity:99% HPLC Package:25KG;200KG;5KG;1KG;1T More...
• CB Index:58
• Related Information:Catalog(9958)