≤20mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide
外見
crystalline solid
酸解離定数(Pka)
9.13±0.20(Predicted)
色
Light yellow to orange
説明
Angiotensin-converting enzyme 2 (ACE2) is an enzyme that is cardioprotective and renoprotective. Resorcinolnaphthalein increases the activity of ACE2 in vitro (EC50 = 19.5 μM). Activation of ACE2 in rats produces a decrease in blood pressure and improvement in cardiac function. In spontaneously hypertensive rats it produces a reversal of myocardial, perivascular, and renal fibrosis.
