2-Phenyl-4-quinolinecarboxylic acid and its derivatives can show antipyretic, analgesic, anti-oxidative, and anti-inflammatory properties. It is also a powerful antimicrobial agent. 2-Phenyl-4-quinolinecarboxylic acid on reaction with 5-aryl-2,3-dihydro-2,3-furandiones yields β-aroylpyruvoyl hydrazide of 2-phenyl-4-quinolinecarboxylic acid.