Chloromethyl 4-chlorophenyl sulfide was used to study the solvolysis of chloromethyl phenyl sulfide [(phenylthio)methyl chloride] and itsp-chloro-derivative in a wide range of hydroxylic solvents. It was used as starting reagent in the synthesis of (4-chlorophenylthio) methyl acetate. It was used as alkylating reagent in microwave-assisted synthesis of 2-amino-imidazo[1,2-a]pyridine derivatives.