Chlorodi(2-furyl)phosphine is a reactant in the synthesis 2, 2?-bis (di-2-furylphosphino)-1, 1?-binaphthalene. Chlorodi(2-furyl)phosphine is a reactant that is used in the synthesis of centrostereogenic 1,3-bidentate ferrocenyldiphosphane ligands, Ferrocene-based chiral diphosphine, and phosphine containing amino acids. In addition, Chlorodi(2-furyl)phosphine can be used as a reactant for α-Arylation of aldehydes, stereoselective sigmatropic rearrangement of acyclic allylic phosphinites and hydrophosphination of functionalized alkenes