trans/cis Resveratrol-D4

trans-Resveratrol-d4 contains four deuterium atoms at the 2, 3, 5, and 6 positions. It is intended for use as an internal standard for the quantification of trans-resveratrol by GC- or LC-mass spectrometry. Phenolic compounds, particularly flavonoids, from plant sources have long been observed to have antioxidant activity with potential benefits for human health. trans-Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. trans-Resveratrol is also a selective inhibitor of cyclooxygenase 1 (COX-1). It inhibits COX and peroxidase activities of COX-1 with ED50 values of 15 and 3.7 μM, respectively, with essentially no inhibition of the COX activity of COX-2.