Cholecalciferol - 100IU/mg - contains 2.5g/kg active
Biosynth Carbosynth
FC45357
2g
$110
9,10-Secocholesta-5,7,10(19)-trien-3beta-ol
1of7
Properties
Melting point
83-86 °C(lit.)
alpha
105 º (c=0.8, EtOH 25 ºC)
Boiling point
451.27°C (rough estimate)
Density
0.9717 (rough estimate)
vapor pressure
2.0 x l0-6 Pa (20 °C, est.)
refractive index
1.5100 (estimate)
Flash point
14 °C
storage temp.
-20°C
solubility
Practically insoluble in water, freely soluble in ethanol (96 per cent), soluble in trimethylpentane and in fatty oils. It is sensitive to air, heat and light. Solutions in solvents without an antioxidant are unstable and are to be used immediately. A reversible isomerisation to pre-cholecalciferol takes place in solution, depending on temperature and time. The activity is due to both compounds.
P314：Get medical advice/attention if you feel unwell.
Description
Vitamin D aids in the absorption of calcium and has central roles in bone formation and maintenance, hypertension, cancer and immunity. Vitamin D3 is an intermediate form of vitamin D which is obtained from dietary sources, such as fish, or through the conversion of 7-dehydrocholesterol by ultraviolet light. Vitamin D3 is subsequently metabolized to 25-hydroxyvitamin D3 and the active form 1,25-dihydroxyvitamin D3 by cytochrome P450 isoforms in the liver. 1,25-Dihydroxyvitamin D3 binds and activates the vitamin D receptor, which dimerizes with retinoid X receptor isoforms to alter gene expression.
