2-Chloro-3-(4-Methyl-1-piperazinyl)quinoxaline;VUF 10166;Quinoxaline, 2-chloro-3-(4-methyl-1-piperazinyl)-;2-chloro-3-(4-methylpiperazin-1-yl)quinoxaline;VUF 10166 USP/EP/BP;VUF 10166, 10 mM in DMSO
≥26.3 mg/mL in EtOH; insoluble in H2O; ≥38.8 mg/mL in DMSO
form
solid
pka
6.55±0.42(Predicted)
color
Light yellow to yellow
Description
VUF 10166 is a 5-HT3 receptor antagonist. VUF 10166 exhibits partial agonist activity at 5-HT3A receptors at higher concentrations. VUF 10166 is also histamine H4 receptor antagonist.
