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ChemicalBook > CAS DataBase List > Polymyxin B sulfate

Polymyxin B sulfate

  • $29 - $3890
  • Product name:Polymyxin B sulfate
  • CAS:1405-20-5
  • MF: C56H100N16O17S
  • MW:1301.56
  • EINECS:215-774-7
  • MDL Number:MFCD00270609
  • Synonyms:POLYMYXIN B;POLYMYXIN-B 2,5-SULFATE;POLYMYXIN B SULFATE;POLYMYXIN B SULFATE, BACILLUS POLYMYXA;POLYMYXIN B SULFATE SALT;POLYMYXIN B SULPHATE;POLYMYXIN B (PMB);POLYMIXIN B SULFATE
Price
  • Brand:Sigma-Aldrich
  • Product number:5291
  • Product namePolymyxin B Sulfate - CAS 1405-20-5 - Calbiochem
  • Purity:
  • Packaging:5gm
  • Price:$362
  • Updated:2020/8/18 13:37:41
  • Buy:Buy
  • Brand:Sigma-Aldrich
  • Product number:1547007
  • Product namePolymyxin B sulfate
  • Purity:
  • Packaging:200mg
  • Price:$366
  • Updated:2021/3/22 19:32:44
  • Buy:Buy
  • Brand:Sigma-Aldrich
  • Product number:P1004
  • Product namePolymyxin B sulfate salt
  • Purity:
  • Packaging:25mu
  • Price:$398
  • Updated:2020/8/18 13:37:41
  • Buy:Buy
  • Brand:TCI Chemical
  • Product number:P1923
  • Product namePolymyxin B Sulfate
  • Purity:
  • Packaging:1g
  • Price:$100
  • Updated:2021/3/22 18:33:11
  • Buy:Buy
  • Brand:TCI Chemical
  • Product number:P1923
  • Product namePolymyxin B Sulfate
  • Purity:
  • Packaging:5g
  • Price:$346
  • Updated:2021/3/22 18:33:10
  • Buy:Buy
Properties
  • Melting point:217-220°C (dec.)
  • storage temp. 2-8°C
  • solubility H2O: 50 mg/mL
  • form powder
  • pkapKa 8.9 (Uncertain)
  • color colorless or slightly yellow
  • PHpH (10g/L, 25℃) : 4.5~7.0
  • optical activity[α]/D 20/D (Rotation: -2.3 +/- 0.2 degrees)
  • Water Solubility Soluble in water at 50mg/ml/n
  • Merck 14,7573
  • CAS DataBase Reference1405-20-5(CAS DataBase Reference)
  • EPA Substance Registry SystemPolymixin B sulfate (1405-20-5)
Safety Information
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • H302:Harmful if swallowed
  • Precautionary statements
  • P264:Wash hands thoroughly after handling.
  • P264:Wash skin thouroughly after handling.
  • P270:Do not eat, drink or smoke when using this product.
  • P330:Rinse mouth.

Description

The polymyxins are cationic peptides originally isolated from B. polymyxa. They bind and kill Gram-negative bacteria. The B series of polymyxins consist of a cyclic heptapeptide and a tripeptide side chain acylated at the amino terminus by a fatty acid. Polymyxin B (sulfate) is a mixture of at least four closely related components, polymyxin B1 to B4, with polymyxin B1 and B2 being the two major components. Polymyxin B (sulfate) has rapid in vitro bactericidal activity against major multidrug-resistant Gram-negative bacteria, such as P. aeruginosa, A. baumannii, and K. pneumoniae.


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