Padanamide A is a bacterial metabolite originally isolated from a marine
Streptomyces species.
1 It is active against five strains of
P. falciparum (EC
50s = 160-340 nM), is not cytotoxic to HEK293 or HepG2 human cell lines, but is cytotoxic to Jurkat T lymphocytes with an IC
50 value of approximately 60 μg/ml.
2,3
