Protein kinase C? (PKC?) is a calcium-independent, phospholipid- and diacylglycerol-dependent serine/threonine kinase involved in diverse signaling pathways, including those involved in neuronal signaling, cytoskeletal function, and inflammation. PKC? inhibitor peptide is a synthetic peptide corresponding to an amino acid sequence found in the amino terminal C2 domain of most mammalian forms of PKC?. It selectively and reversibly inhibits the translocation of PKC? to intracellular membranes, blocking activation. PKC? inhibitor peptide is commonly used in cells to evaluate the role of PKC? in various cellular responses.
